Search results for " Brain Diseases"

showing 3 items of 3 documents

Intestinal ischemia/reperfusion promotes brain damage via microglia activation: can we do something now?

2012

MalePathologymedicine.medical_specialtycomplicationsetiologyBrain damageAnimals Brain Diseases; etiology Intestines; blood supply Ischemia; complications Male Memory Disorders; etiology Microglia; physiology Reperfusion Injury; complicationsCritical Care and Intensive Care MedicineIschemiamedicineAnimalsischemia reperfusion brain damageBrain DiseasesMemory DisordersMicrogliabusiness.industryIntestinal ischemiaSettore MED/27 - Neurochirurgiablood supplyIntestinesmedicine.anatomical_structureReperfusion InjuryphysiologyMicrogliamedicine.symptombusiness
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Neural networks engaged in milliseconds and seconds time processing: evidence from transcranial magnetic stimulation and patients with cortical or su…

2009

Here, we review recent transcranial magnetic stimulation studies and investigations in patients with neurological disease such as Parkinson's disease and stroke, showing that the neural processing of time requires the activity of wide range-distributed brain networks. The neural activity of the cerebellum seems most crucial when subjects are required to quickly estimate the passage of brief intervals, and when time is computed in relation to precise salient events. Conversely, the circuits involving the striatum and the substantia nigra projecting to the prefrontal cortex (PFC) are mostly implicated in supra-second time intervals and when time is processed in conjunction with other cognitiv…

Parkinson's diseaseNerve netParkinson's diseaseRepetitive transcranial magnetic stimulationmedicine.medical_treatmentParkinson's disease; Repetitive transcranial magnetic stimulation; Stroke; Time perception; Timing; Transcranial magnetic stimulation;Time perceptionReviewGeneral Biochemistry Genetics and Molecular BiologyNOStimulus modalityCerebral Cortex; Humans; Time Perception; Brain Diseases; Transcranial Magnetic Stimulation; Nerve NetmedicineHumansTimingBRAINPrefrontal cortexCerebral CortexBrain DiseasesSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryCognitionTime perceptionmedicine.diseaseTIMEStrokeTranscranial magnetic stimulationmedicine.anatomical_structureCerebral cortexSettore MED/26 - NeurologiaNerve NetGeneral Agricultural and Biological SciencesbusinessNeuroscienceTranscranial magnetic stimulationPhilosophical Transactions of the Royal Society B: Biological Sciences
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Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome

2011

Background:  To report on the first multicenter Italian experience with rufinamide as adjunctive drug in children, adolescents and young adults with refractory childhood-onset epileptic encephalopathies other than Lennox-Gastaut syndrome. Methods:  Thirty-eight patients (19 males, 19 females), aged between 4 and 34 (mean 13.7 ± 8.3, median 12.5), all affected by different types of childhood-onset refractory epileptic encephalopathies other than Lennox-Gastaut syndrome, were treated with rufinamide as adjunctive drug for a mean period of 11.4 months (range 3-26 months). Results:  Fifteen of 38 patients (39.5%) had a ≥50% seizure reduction in co…

AdultMalePediatricsmedicine.medical_specialtyAdolescentrufinamideRufinamideIrritabilityrefractory seizures; rufinamide; epileptic encephalopathies-childhoodYoung AdultRefractoryepileptic encephalopathies-childhoodrefractory seizuresrufinamideMedicineHumansYoung adultAdverse effectChildPreschoolepileptic encephalopathies-childhoodBrain DiseasesEpilepsybusiness.industryEpileptic encephalopathies-childhood; Refractory seizures; RufinamideTriazolesmedicine.diseaseSettore MED/39 - Neuropsichiatria Infantilerefractory seizuresMigraineepileptic encephalopathies-childhood refractory seizures rufinamideNeurologyAnesthesiaChild PreschoolVomitingAnticonvulsantsFemaleNeurology (clinical)medicine.symptombusinessEpileptic encephalopathies-childhood; Refractory seizures; Rufinamide; Adolescent; Adult; Anticonvulsants; Brain Diseases; Child; Child Preschool; Epilepsy; Female; Humans; Male; Triazoles; Young Adult; Neurology (clinical); NeurologyLennox–Gastaut syndromemedicine.drug
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